Woman

Dr. Sigal Liraz-Zaltsman

Senior lecturer in the Department of Communication Disorders

Contact

לעמוד המרצה בעברית

About

Dr. Liraz-Zaltsman is a physical therapist with extensive experience in neurological rehabilitation. Currently, she is a neuroscientist leading a research group on traumatic brain injuries at the Yosef Segol Brain Research Center, Sheba Tel Hashomer Medical Center. She also manages the national brain tissue database.

Education

PhD

Brain Research - Hebrew University of Jerusalem

MA

Neurobiology - Hebrew University of Jerusalem

BA

Physiotherapy - Tel Aviv University

Teaching Areas

Anatomy and Physiology of the Nervous System, General Anatomy and Musculoskeletal Anatomy, Neurology.

Research interests

Long-term effects of traumatic brain injury, understanding mechanisms and long-term processes that turn traumatic brain injury into chronic neurodegenerative disease, developing pharmacological treatments to improve cognitive decline after traumatic brain injuries, the impact of lifestyle (e.g., physical activity) on cognitive decline following head injuries.

Selected Publications

Liraz-Zaltsman S, Friedman-Levi Y, Shabashov-Stone D, Gincberg G, Atrakcy-Baranes D, Joy MT, Carmichael ST, Silva AJ, Shohami E. Chemokine Receptors CC Chemokine Receptor 5 and C-X-C Motif Chemokine Receptor 4 Are New Therapeutic Targets for Brain Recovery after Traumatic Brain Injury. J Neurotrauma. 2021 Jan 25. doi: 10.1089/neu.2020.7015. PMID: 33256497
Friedman-Levi Y, Liraz-Zaltsman S* (Equal contribution), Shemesh C, Rosenblatt K, Kesner EL, Gincberg G, Carmichael ST, Silva AJ, Shohami E. Pharmacological blockers of CCR5 and CXCR4 improve recovery after traumatic brain injury. Exp Neurol. 2021 Apr;338:113604. doi: 10.1016/j.expneurol.2021.113604. Epub 2021 Jan 14. PMID: 33453212
Joy MT, Ben Assayag E, Shabashov-Stone D, Liraz-Zaltsman S, Mazzitelli J, Arenas M, Abduljawad N, Kliper E, Korczyn AD, Thareja NS, Kesner EL, Zhou M, Huang S, Silva TK, Katz N, Bornstein NM, Silva AJ, Shohami E, Carmichael ST. CCR5 Is a Therapeutic Target for Recovery after Stroke and Traumatic Brain Injury. Cell. 2019 Feb 21;176(5):1143-1157.e13. doi: 10.1016/j.cell.2019.01.044
Liraz-Zaltsman S, Slusher b, Atrakchi-Baranes D, Rosenblatt K, Friedman-Levi Y, SilvaA.J, Biegon A, Shohami E. Enhancement of brain D-serine mediates recovery of cognitive function after TBI. Journal of Neurotrauma 2017.
Shelly S, Liraz Zaltsman S *(Equal contribution),, Ben-Gal O, Dayan A, Ganmore I, Shemesh C, Atrakchi D, Garra S, Ravid O, Rand D, Israelov H, Alon T, Lichtenstein G, Sharabi S, Last D, Gosselet F, Rosen V, Burstein G, Friedlander A, Harel R, Vogel G, Schnaider Beeri M, Mardor Y, Lampl Y, Fleminger G, Cooper I. Potential neurotoxicity of titanium implants: Prospective, in-vivo and in-vitro study . Biomaterials. 2021 Jul 24;276:121039 PMID: 34352627